Changes of autonomic and sensory function during 24 weeks of antiviral treatment in patients with chronic HCV infection
L Csihi, J Osztovits, E Horváth, J Tax, T Horváth, T Csák, T Tóth, M Abonyi, J Fehér, P Kempler, M Kollai, F Szalay · Zeitschrift für Gastroenterologie · 2009 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and aim: Neurological complications of chronic Hepatitis C virus (HCV) infection are known predominantly in the peripheral nervous system. Symptoms of sensomotor neuropathies mainly change for the better during anti-HCV treatment, but they can worsen, as well. It is not known, how autonomic function changes during inteferon+ribavirin treatment. Methods: 24 HCV PCR positive, treatment-naive patients were enrolled in the study (age=46.5±10.6 years). Cardiovagal autonomic function was assessed by determining heart rate variability (HRV) and spontaneous baroreflex sensitivity (BRS) indices. Heart rate was…