Host cell signalling inhibitors against helicobacter pylori
Z Varga, Z Greff, J Pató, P Bánhegyi, L Őrfi, A Ishiguro, I Peták, R Schwab, G Kéri, J Crabtree · Zeitschrift für Gastroenterologie · 2009 · Heft 05
Bibliografische Angaben
Zusammenfassung
More than 50% of the world population is infected by Helicobacter pylori nowdays. Although in most cases it doesn't causes any symptoms it's a significant risk factor in the development of gastric ulcer or gastric carcinoma. Elimination of the bacteria can be attained by the combination of at least three drugs and it may also causes several side effects. It's beyond doubt that a new drug showing good efficacy without side effects is needed. Kinase inhibitors have proved their usefulness in the treatment of cancer inhibiting cell proliferation via inhibition of intracellular signaling system. Moreover host cell k…
