A teaching film, video library and online certification for the Unified Huntington's Disease Rating Scale Total Motor Score
R Reilmann, R Roos, A Rosser, Y Grimbergen, P Kraus, D Craufurd, M Dose, A Weindl, E Howard, D Ecker, S Bohlen, JM Burgunder, HW Lange, GB Landwehrmeyer · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: Clinical assessment of motor symptoms in Huntington's Disease (HD) is commonly performed using the Unified Huntington's Disease Rating Scale-Total Motor Score (UHDRS-TMS) (HSG 1996). Clinical diagnosis of HD is based on the presence of characteristic motor symptoms in the UHDRS-TMS. Therefore results of clinical trials are limited by (1) possible subjective error of raters (inter-rater and intra-rater variability), (2) the limited sensitivity of the categorical rating scale (non-continuous measure), and (3) insensitivity in pre-manifest subjects (de Boo et al., 1998). Objective: In order to increase…
