Phosphatidylethanol: Normalisation during detoxification, gender aspects and correlation with other biomarkers and self-reports
FM Wurst, N Thon, S Aradottir, S Hartmann, GA Wiesbeck, O Lesch, K Skala, M Wolfersdorf, W Weinmann, C Alling · Suchttherapie · 2009 · Heft 09
Bibliografische Angaben
Zusammenfassung
Aims: Phosphatidylethanol (PEth) is a direct ethanol metabolite, attracting attention as biomarker of ethanol intake. Aims of the presented studies are: 1) To further characterise the normalisation of PEth in lager samples and 2) to elucidate potential gender differences and 3) the correlation with other biomarkers and self-reports. Patients and methods: Fifty-seven alcohol dependent patients (ICD 10 F 10.25; f=9, m=48) at three study sites age 43.56 years, gamma glutamyl transpeptidase (GGT) 209.61 U/L, mean corpuscular volume (MCV) 97.35 fL, carbohydrate deficient transferrin (%CDT) 8.68, 1452.29g ethanol inta…