The influence of genetics on white matter lesion load in patients with vascular subcortical dementia compared to patients with Alzheimer disease and persons without cognitive impa…
P Kelemen, H Kölsch, R Seitz, B Krumm, L Frölich, F Hentschel · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2007 · Heft 05
Bibliografische Angaben
Zusammenfassung
Ziele: Ischemic neuronal disintegration of the brain tissue is a main risk factor for the developement of a vascular dementia (VD). Because of the complexity of cerebrovascular and other factors it is not possible to describe the whole variance of the incidence of VD merely by genetic polymorphisms. Nevertheless there is hope to identify the contribution of genetic markers in VD. Methode: Data of clinically, neuropsychologically, neuroradiologically and genetically examined patients (n=236) of a memory clinic were analysed upon the interrelation of clinical diagnosis according to ICD-10 and genetics, differentia…