Surfactant Replacement or Open Lung Concept? Comparison of two treatment strategies in neonatal ARDS
A Hilgendorff, T Schaible, L Gortner, T Bähner, M Ebsen, C Ruppert, I Reiss · Zeitschrift für Geburtshilfe und Neonatologie · 2007 · Heft 06
Bibliografische Angaben
Zusammenfassung
Objective: Several concepts of treatment in neonatal acute respiratory distress syndrome have been proposed in the last years including different ventilation concepts as well as surfactant replacement strategies. The present study compared the effects of an intensified open lung ventilation concept with a conventional ventilation strategy combined with administration of two different surfactant preparations on lung function and surfactant homoeostasis. Design and subjects: After repeated whole-lung saline lavage, 16 newborn piglets were assigned to either open lung concept positive pressure ventilation (PPVOLC;…
