Dehydroepiandrosterone sulfate and common carotid intima-media thickness in patients with type 2 diabetes mellitus
M Vasiliadis, M Papaioakim, I Heliopoulos, T Gioka, A Tsiligiris, M Toromanidou, M Nikelli, E Pagalos · Diabetologie und Stoffwechsel · 2007 · Heft 07
Bibliografische Angaben
Zusammenfassung
Backgrounds/Aims Cardiovascular disease (CVD) is the primary cause of mortality in patients with diabetes mellitus (DM). Studies have shown an inverse relationship between plasma levels of dehydroepiandrosterone sulfate (DHEA-S) and coronary artery disease. It has been reported that DHEA-S levels are negatively correlated with common carotid intima-media thickness (CCIMT) with type 2 DM but only in men. We examined the association between endogenous DHEA-S and CCIMT, in patients of both sexes with type 2 DM. Methods Serum DHEA-S concentration was measured in 169 participants with type 2 DM (102 females and 67 ma…