How imprecise may the measurement of fetal nuchal translucency be without worsening the firsttrimester screening?
P Schmidt, I Staboulidou, C Hörmansdörfer, M Elsässer, P Hillemanns, A Scharf · Ultraschall in der Medizin - European Journal of Ultrasound · 2007 · Heft 10
Bibliografische Angaben
Zusammenfassung
Objective: The firsttrimester screening (FTS) has a trisomy 21 detection rate of about 90%. Despite a profound training, the pracitically reached measurement quality of the nuchal translucency (NT) is probably not optimal. This study investigated the impact of measurement errors on the FTS. Methods: The data of 10116 combined FTSs had been acquired in a multicenter study. Risk assessment was performed by the JOY software in accordance to Nicolaides. To investigate the impact of measurement errors, the NT values were artificially altered and the adjusted risks were recalculated. Test performance parameters were o…