An fMRI study of changes in the functional network of action monitoring associated with psychotic passivity symptoms

Introduction: It has been proposed that disturbed perception of own actions in schizophrenia results from defective action monitoring. In a previous fMRI-study we demonstrated that monitoring of temporal congruence between intended and perceived actions involves a neural network comprising medial (BA10) and lateral (BA 45, 46) prefrontal and inferior parietal (iPC) (BA40) cortices. Here we applied the same experimental design to test for a correlation between functional changes within this network and the occurrence of passivity symptoms in schizophrenia. Methods: The basis of the boxcar fMRI-design was a simple…