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Neuronal correlates of movement disorders in normal pressure hydrocephalus (NPH)-before and after therapeutic lumbar puncture

M Ebke, E Küstermann, B Neubauer, G Schwendemann, M Herrmann, D Leibfritz · Klinische Neurophysiologie · 2008 · Heft 04

Dokument
1137729
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
M Ebke, E Küstermann, B Neubauer, G Schwendemann, M Herrmann, D Leibfritz
Ausgabe
Heft 04 / 2008
Seiten
–
Erschienen: 2008-04-08 00:00:00
ISSN
1434-0275

Zusammenfassung

Introduction: Normal pressure hydrocephalus (NPH) affects predominantly elderly people possing major impact gait problems which improve upon guidance. Objective and Hypothesis: It has been hypothesised that reduced resorption of CSF leads to penetration into the frontal reducing the cerebral blood flow (CBF). We document blood-oxygen level dependend (BOLD)-signal changes with functional magnetic resonance imaging (fMRI) before and after lumbar puncture (LP). In order to explore the neuronal correlates, subjects were asked to perform imaginary foot movement and walking tasks. We expected a changed brain activity…

Schlagworte

After Movement Blood Movement Disorders Germany Klinische Neurophysiologie