Bioactive agents against systemic low-grade inflammation
Z Mihály, V Hegedüs, D Gerő, G Bekő, G Lotz, K Szentmihályi, K Monostory, A Szijártó, A Blázovics · Zeitschrift für Gastroenterologie · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: Free radicals and lipid peroxides assign a systemic low-grade inflammation. NF-κB regulated by reactive oxygen radicals, influence the transcription of many target genes, like iNOS, COX-2, and TNF-α. Bioactive agents e.g. vitamins, flavonoids and polyphenols may reduce the inflammation processes. Our aim was to determine the advantages of a functional product containing Beta vulgaris var. rubra and Daucus carota (BVD) in „short term“ alimentary fatty liver rodent model. Methods: Male Wistar (N=30) rats were kept on conventional chow with or without high fat supplementation (2% cholesterol, 0.5% cho…