CareLit Fachartikel

Ulcerative colitis and Crohn's disease associated discriminatory gene patterns in biopsies and peripheral blood samples

F Sipos, O Galamb, N Solymosi, S Spisák, T Krenács, Z Tulassay, B Molnár · Zeitschrift für Gastroenterologie · 2008 · Heft 05

Dokument
1138092
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
F Sipos, O Galamb, N Solymosi, S Spisák, T Krenács, Z Tulassay, B Molnár
Ausgabe
Heft 05 / 2008
Seiten
–
Erschienen: 2008-05-15 00:00:00
ISSN
0044-2771
DOI
10.1055/s-2008-1079698

Zusammenfassung

Introduction: Histological diagnosis of IBD subtypes unambiguou even today. Based on immune cell trafficking between mucosa layers in colon, tissue-specific biological information may be detected in peripheral blood (PB). Aims: To establish and to compare the characteristic gene expression profiles (GEP) of IBD in PB and in colonic biopsies for diagnostic purposes. Methods: Biopsies and peripheral blood samples (PBS) from 12 active ulcerative colitis (UC)(12/6), 9 active Crohn's colitis (CD)(9/5) and 11 healthy control (11/11) patients were taken. The isolated and labelled mRNA was hybridized to Affymetrix whole…

Schlagworte

Blood Chemokine C- Diagnosis After Zeitschrift für Gastroenterologie