CareLit Fachartikel
Hepatocytes retain apical polarity during proliferation in liver regeneration
SK Hammad, JG Hengstler, P Godoy, W Schormann · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Dokument
1138268
CareLit-ID
Jahr
2010
Publikation
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Metadaten
DOI
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Bibliografische Angaben
Zusammenfassung
In vivo hepatocytes polarity is characterized by apical domain (bile canaliculi) and basolateral domain which faces liver sinusoidal cells. Hepatocyte polarity is highly important physiologically in order to maintain liver functions, and is also in pathological conditions through limiting or preventing harmful agents and micro-organisms to invade hepatocytes such as Hepatitis C virus. In liver regeneration, the architecture of the organ is severely altered. However, there are no available in vivo studies concerning hepatocyte polarity during different stages of cell cycle, therefore in this study we have investi…
Schlagworte
Bile Canaliculi
Cell division
Hepatocyte
Mitosis
Polarity
Dipeptidyl Peptidase 4
Architecture
After
Hepatitis
Zeitschrift für Gastroenterologie
