CareLit Fachartikel
Characterization of the lipid droplet-associated protein MLDP in human tissues and in hepatocyte steatosis
M Hashani, M koenig, LM Pawella, P Schirmacher, BK Straub · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Dokument
1138274
CareLit-ID
Jahr
2010
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Eukaryotic cells store excess neutral lipids in lipid droplets (LDs), cell organelles recognized nowadays as highly dynamic subcellular compartments. LD-associated proteins of the so called PAT-family, named after their major constituents perilipin, adipophilin and TIP47, fundamentally regulate lipid storage and utilization. MLDP (“myocardial LD-protein“, perilipin-5), the newest member of this protein family, is reported to be expressed in highly oxidative tissues such as heart, red muscle and liver during fasting. Yet, experiments undertaken so far were mainly conducted in murine tissues and in cell cultures.…
Schlagworte
MLDP
lipid droplet
Adipophilin
Adipocytes
After
Zeitschrift für Gastroenterologie
