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K-complex associated thalamic BOLD signal changes revealed by EEG/fMRI
K Jahnke, H Laufs, F von Wegner, S Borisov · Klinische Neurophysiologie · 2010 · Heft 03
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1138468
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2010
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Introduction: Recent studies suggest that the K-complex (KC) reflects a synchronized and cortically generated state [1]. Electrophysiological data support the role of the thalamus in the mediation of graphoelements (sleep spindles, delta waves) following the K-complex [2]. We hypothesized that KC detected with scalp EEG during stage 2 sleep correlate with thalamic (volume of interest) blood oxygen level-dependent (BOLD) signal changes. Material and Methods: We analyzed twenty-five healthy, not formally sleep-deprived, eyes-closed resting volunteers studied with functional magnetic resonance imaging at 3T and sim…
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Klinische Neurophysiologie
