Interscapular fat is strongly associated with insulin resistance

Context: Subcutaneous abdominal adipose tissue (SCAAT), visceral adipose tissue (VAT), fat in the neck area [interscapular fat (IF)], and liver fat (LF) are associated with metabolic traits related to insulin resistance. Whole body magnetic resonance imaging (MRI) and spectroscopy (MRS) offer a unique approach to quantify fat depots in larger cohorts. Objective: To study i) the impact of the aforementioned fat depots on insulin sensitivity (IS) in a cross sectional design and ii) changes in these fat depots and in IS during a lifestyle intervention (LI). Design: 187 subjects were included in the cross-sectional…