Fibrosis markers (serum hyaluronic acid, procollagen-III-peptide, pasma transforming growth factor-beta) and transient elastography (fibroscan) in chronic HCV infection
G Pár, A Vincze, T Berki, A Miseta, L Pajor, L Kereskai, Z Szereday, A Nagy, B Hunyady, A Pár · Zeitschrift für Gastroenterologie · 2010 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Even mild chronic hepatitis C may be associated with severe fibrosis, that needed peg-interferon + ribavirin (P/R) therapy. We have tudied fibrosis markers and transient elastography (TE)(FibroScan) to assess liver fibrosis by these non-invasive tools. Patients and Methods: 119 HCV-patients (51 male, 68 female) have been enrolled, of them 75 had biopsy-proven chronic hepatitis C, 49 treated with P/R, 20 patients had cirrhosis, 20 individuals were symptomfree HCV-carriers with persistently normal alanine aminotransferase (PNA), 25 blood donors served as controls. Serum HCV-RNA has been determined by P…
