CareLit Fachartikel

Adaption of the Roche Septifast system for the early detection of neonatal sepsis in very low birthweight infants

A Berger, I Altiok, T Mechtler, M Langgartner, J Böhm, K Herkner, A Pollak, D Kasper · Klinische Pädiatrie · 2010 · Heft 06

Dokument
1138796
CareLit-ID
Jahr
2010
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
A Berger, I Altiok, T Mechtler, M Langgartner, J Böhm, K Herkner, A Pollak, D Kasper
Ausgabe
Heft 06 / 2010
Seiten
–
Erschienen: 2010-06-09 00:00:00
ISSN
0300-8630

Zusammenfassung

Introduction: The gold standard for diagnosis of bacterial sepsis is a positive blood culture. However, results are usually not available before to 48 to 72h and pathogens are detected in only 25% of patients. Molecular assays for the detection of DNA in the blood have been tested as new diagnostic tools for early identification of bacterial sepsis in adults. Objective: To adapt and evaluate a commercially available PCR system for use in neonatology by using small blood volumes. Materials and Methods: Blood specimens of 38 VLBW infants (mean±SD, range: 829g±242, 350–1150g) with clinical sepsis suspicion were ana…

Schlagworte

Blood Blood Culture Sepsis Blood Volume Diagnosis Bacteria Klinische Pädiatrie