Is zoom-endoscopic subaqual mucosa evaluation able to replace biopsy in the diagnostics of acute tissue rejection in patients with small intestine transplantation?

Acute tissue rejection, infection and relapse of Crohn's disease are possible complications after small intestine transplantation. Questions: 1. Is zoom-endoscopic evaluation sufficient for the identification of tissue rejection? 2. Is the “optical biopsy“ able to replace time-consuming histological findings in emergency situations? 3. Is it possible to replace zoom-endoscopy via special zoom devices by subaqual tissue evaluation with standard devices? 4. Is it sufficient to inspect only the transplant stoma? Methods: Prospective study on 6 patients after small intestine transplantation. Endoscopic surveillance…