CareLit Fachartikel

Soluble urokinase plasminogen activator receptor is a marker for severity of liver fibrosis in hepatitis C infection

ML Berres, B Schlosser, T Berg, C Trautwein, HE Wasmuth · Zeitschrift für Gastroenterologie · 2010 · Heft 08

Dokument
1138975
CareLit-ID
Jahr
2010
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig

Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
ML Berres, B Schlosser, T Berg, C Trautwein, HE Wasmuth
Ausgabe
Heft 08 / 2010
Seiten
–
Erschienen: 2010-08-03 00:00:00
ISSN
0044-2771

Zusammenfassung

Aims: The plasminogen activator system and its receptors have been implicated in different immune mechanism and serum levels of the soluble urokinase plasminogen activator receptor (suPAR) are elevated in infectious and immune mediated diseases. However, while the importance of the coagulation cascade has been suggested in liver fibrogenesis due to viral heatitis, the role of the fibrinolytic pathway remains unclear. We evaluated the association of serum levels of suPAR with established parameters of liver fibrosis in two independent HCV infected cohorts. Patients and methods: 146 patients with chronic HCV infec…

Schlagworte

Berlin Biopsy Association Diagnosis Hepatitis Zeitschrift für Gastroenterologie