Soluble endoglin and inhibin A as potential first trimester markers to predict preeclampsia
MU Baumann, NA Bersinger, M Mohaupt, L Raio, A Spreu, DV Surbek · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective: In the last few years, serious efforts have been made to find biochemical markers in asymptomatic pregnant women, which allow to predict the risk of preeclampsia. Soluble endoglin (sEng) is a co-receptor for transforming growth factor-beta1 and –3, while inhibin A is a member of the transforming growth factor beta family. In pregnancy, they are predominantly secreted by the placenta. Further, when compared to controls, they both show increased midtrimester serum levels in pregnancies with subsequent preeclampsia. Information on first trimester serum levels of these serum markers is scarce. The aim of…
