Association between drug use and acute immune thrombocytopenia in adults: a case-control study from the Berlin Pharmacovigilance Center PVZ-FAKOS
H Kurtal, E Bronder, A Klimpel, F Andersohn, E Garbe · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background and Aim: Drug induced acute immune thrombocytopenia (ITP) can be triggered by numerous medications. Aim of our study was to quantify the risk of acute ITP for a wide range of drugs. Materials and Methods: Case-control study including 135 cases of acute ITP leading to hospitalization and 731 control patients aged 18 years and older. Cases were defined as patients with idiopathic or symptomatic ITP and patients with suspected drug induced ITP who had a platelet count ≤100.000/µl. Patients with heparin-induced immune thrombocytopenia were not included as cases. Cases and controls were recruited in 51 hos…