7 Tesla 3D-MP-FLAIR and 3D-MP-DIR: Lesion Detection in Multiple Sclerosis
WL de Graaf, F Visser, MP Wattjes, JJ Zwanenburg, PJW Pouwels, JJG Geurts, CH Polman, F Barkhof, PR Luijten, JA Castelijns · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · Heft 11
Bibliografische Angaben
Zusammenfassung
Purpose: In Multiple Sclerosis (MS) increasing attention is given to cortical demyelination. At 1.5T, cortical lesions are best visualized with Fluid Attenuated Inversion Recovery (FLAIR) and Double Inversion Recovery (DIR) sequences. At higher field, the gain in SNR can be used to increase spatial resolution, which may enhance the sensitivity of these sequences. In this study FLAIR and DIR are compared with 2D PD/T2, and 3D-T1 weighted imaging at 3 and 7 Tesla. Materials and Methods: 15 MS patients and 5 healthy volunteers were examined at 3T (GE HDxt) and 7T (Philips, Achieva), at time intervals