Treatment of HCV Genotype 1 (G1) infection with PEG-IFN α-2b and Ribavirin (RBV): age and gender related differences in viral response and RBV action
S Mauss, G Teuber, E Zehnter, MP Manns, T Dahhan, U Meyer, K Dach, M Bilzer, G Tossing, D Hueppe · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and Aims: Recently, higher SVR rates in female genotype (G) 1 patients (pts) have been reported in the IDEAL study. In order to better understand the main factors associated to those results, we evaluated predictors of viral response by gender and age. Methods: Data from the German Peg-IFNα-2b/RBV observational study were retrospectively analyzed. This real-life cohort study assessed the safety and efficacy of pts treated with Peg-IFN α-2b 1.5µg/kg/wk+weight-based RBV (800–1200mg/day) for up to 48 wks at 285 sites. Pts who discontinued for non-response or for any other reasons were included in the ana…
