Efficacy of repetitive cathodal transcranial direct current stimulation of the visual cortex in the prophylaxis of menstrual migraine

Background and purpose: Patients with menstrual migraine often suffer from psychological strain. Preventive therapy is indicated in about a third of patients, and although a broad range of pharmaceutical option exists, there is an increasing interest concerning non-pharmaceutical alternatives. According to this, the repetitive cathodal transcranial direct current stimulation (rc-tDCS) of the visual cortex as non-invasive brain stimulation might be a therapeutic alternative. The present study aimed to explore the efficacy of rc-tDCS as a prophylactic treatment in migraineurs and to decrease the frequency or short…