Chemerin serum levels are associated with parameters of obesity and vascular inflammation in children
K Landgraf, D Friebe, J Kratzsch, K Dittrich, G Herberth, W Kiess, S Erbs, A Körner · Diabetologie und Stoffwechsel · 2011 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective: The new adipokine chemerin has been shown to play a role in adipocyte differentiation and is associated with parameters of obesity and metabolic syndrome in adults. In this study, we aimed to analyze chemerin serum levels and their association to measures of obesity and early-onset metabolic and vascular sequelae in children. Methods and results: Serum levels of chemerin were quantified by ELISA in 69 lean and 105 obese children of the Leipzig Atherobesity childhood cohort. Associations of chemerin with detailed metabolic and cardiovascular parameters were assessed. We identified highly significant as…
