Changes in liver stiffness in patients with chronic hepatitis C with or without antiviral treatment

Aims: To determine the changing of liver fibrosis using transient elastography (TE) in patient with chronic hepatitis C (CHC), who achieved sustained virological response (SVR) or only biochemical response (BR: HCV RNA positive, but normal ALT); comparing with non-responders (NR) and non-treated (NT) patients. Material and methods: LS was measured in 141 HCV infected patients. TE was made before the treatment, and during the follow-up in 11 of 84 pegylated interferon + ribavirin treated patients, who achieved SVR, in 40 patients with BR, and in 33 NRs, respectively. LS was determined in 57 untreated patients rep…