Delayed gastric emptying determines prognosis in critically ill patients with sepsis
T Liebregts, B Adam, C Greis, T Neumann, R Erbel, G Holtmann · Zeitschrift für Gastroenterologie · 2011 · Heft 08
Bibliografische Angaben
Zusammenfassung
Background: Delayed gastric emptying (GE) is a frequent finding in critically ill patients and potentially associated with increased rates of morbidity and mortality. While animal models suggest that bacterial endotoxin- induced cytokine release is associated with gastrointestinal motility dysfunction in sepsis, clinical data is lacking. We hypothesized that delayed GE is associated with length of stay, overall survival and linked to immune activation as reflected by cytokine release. Methods: Twenty mechanically ventilated patients with sepsis were recruited within 48h of admission to ICU at a tertiary care hos…