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Lactoferrin gene expression upregulation in liver during turpentine oil- or bacterial LPS-induced acute phase reaction

G Ahmad, GZK Sial, P Ramadori, J Dudas, DS Batusic, G Ramadori · Zeitschrift für Gastroenterologie · 2012 · Heft 01

Dokument
1140466
CareLit-ID
Jahr
2012
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
G Ahmad, GZK Sial, P Ramadori, J Dudas, DS Batusic, G Ramadori
Ausgabe
Heft 01 / 2012
Seiten
–
Erschienen: 2012-01-09 00:00:00
ISSN
0044-2771

Zusammenfassung

Introduction: Lactoferrin (Ltf) is a monomeric glycoprotein which is present in different body fluids including serum. Multifunctional healing abilities of Ltf have been documented in a huge number of publications mainly in the last three decades but no single study has conclusively described the serum sources of this protein particularly during the acute phase reaction (APR). In the current work the role of liver as a source of serum Ltf was investigated during an induced APR. Methods: Male wild type C57Black6 mice 6–8 weeks old were injected intramuscularly 10ml/kg turpentine oil (TO) or intraperitoneally 50μg…

Schlagworte

Acute phase reaction Disease Inflammation Injury Iron Lactoferrin Liver Therapy Acute-Phase Reaction After Cytokines Cytokine Work Zeitschrift für Gastroenterologie