Lactoferrin gene expression upregulation in liver during turpentine oil- or bacterial LPS-induced acute phase reaction
G Ahmad, GZK Sial, P Ramadori, J Dudas, DS Batusic, G Ramadori · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: Lactoferrin (Ltf) is a monomeric glycoprotein which is present in different body fluids including serum. Multifunctional healing abilities of Ltf have been documented in a huge number of publications mainly in the last three decades but no single study has conclusively described the serum sources of this protein particularly during the acute phase reaction (APR). In the current work the role of liver as a source of serum Ltf was investigated during an induced APR. Methods: Male wild type C57Black6 mice 6–8 weeks old were injected intramuscularly 10ml/kg turpentine oil (TO) or intraperitoneally 50μg…