Liver stiffness in cardiac insufficiency: Is elevated GGT due to cardiac cirrhosis?
C Dietrich, C Viedt-Suelmann, G Millonig, HK Seitz, S Mueller · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: Cardiac insufficiency may severely impair hepatic function either due to congestion or impaired perfusion and eventually leads to cardiac cirrhosis. We recently showed that central venous pressure directly affects liver stiffness (LS) independent of fibrosis stage. In the present study, cardiac and hepatic determinants of increased LS are studied in patients with acute cardiac decompensation. Methods and patients: 100 retrospectively analysed patients (learning cohort) and 14 prospective patients (validation cohort) with acute heart failure, liver tests, echocardiography and LS were sequentially me…