Indocyanine green-augmented diode laser treatment of port wine stains: Clinical and histological evidence for a new treatment option from a randomized controlled trial (RCT)
A Klein, RM Szeimies, W Bäumler, F Zeman, S Schreml, U Hohenleutner, M Landthaler, M Koller, P Babilas · Endoskopie heute · 2012 · Heft 03
Bibliografische Angaben
Zusammenfassung
Complete clearance of port wine stains (PWS) is difficult to achieve, mainly because of the resistance of small blood vessels to laser irradiation. Indocyanine green (ICG)-augmented diode laser treatment (ICG+DL) may overcome this problem. This pilot study evaluates the feasibility of ICG-augmented diode laser therapy of PWS and compares safety and efficacy of ICG+DL to the flashlamp-pumped pulsed dye laser (FPDL). In a prospective randomized controlled clinical study, 31 patients with PWS were treated with FPDL (λem =585nm, 6J/cm2, 0.45ms pulse duration) and ICG+DL (λem=810nm, 20–50J/cm2, 10–25ms pulse duration…