Significant decrease in prevalence of Helicobacter pylori and peptic ulcer disease over a 17-year period
M Varga, B Bittera, J Láng, M Juhász, G Lakatos, P Miheller, E Mihály, A Németh, Z Tulassay, L Herszényi · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: We and others have already suggested that the incidence of Helicobacter pylori (H. pylori) negative peptic ulcer disease (PUD) has increased in the latest years. Aims: to investigate in a retrospective study the prevalence of H. pylori and PUD and to compare etiology, gender and age distribution in PUD in 1995, 2000, 2005 and 2011. Methods: Medical and endoscopic records were retrospectively reviewed with similar data obtained over a 17-year period at the same endoscopic unit with regard to H. pylori status and prevalence of endoscopically proven PUD. Results: The rate of H. pylori positivity decreas…