Association of homoarginine and methylarginines with liver dysfunction and mortality in cirrhotic patients
C Putz-Bankuti, S Pilz, A Meinitzer, W März, K Kienreich, T Stojakovic, M Trauner, TR Pieber, RE Stauber · Zeitschrift für Gastroenterologie · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and Aims: Previous studies suggest that the methylarginines, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), are associated with liver dysfunction and may predict adverse outcomes. Homoarginine, another cationic amino acid derivate, is involved in nitric oxide metabolism and is associated with reduced mortality in patients with high cardiovascular risk. We aimed to investigate the relationships of homoarginine, ADMA and SDMA with Child-Pugh (CP) score, model for end-stage liver disease (MELD) score, and survival in patients with cirrhosis. Methods: We enrolled 94 consecutive…
