CareLit Fachartikel
The Role of selected Redoxins in the Manifestation and Exacerbation of Allergic Airway Inflammation
C Hudemann, EM Hanschmann, CH Lillig, H Renz · Pneumologie · 2012 · Heft 05
Dokument
1141154
CareLit-ID
Jahr
2012
Publikation
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Zusammenfassung
Introduction: Oxidative stress is believed to play a major role in the development of, among others, immunologic diseases. Asthma is a chronic allergic airway disease, and to date it is not clear whether the observed enhanced oxidative stress in asthmatic patients is caused by airway inflammation, or is a causative factor in the pathogenesis of this disease. Several studies have attributed the thioredoxin fold family a major impact in protection of the lung, and deregulation may bring about initiation of Th2-dominant immunity and contribute to the progression or perpetuation of existing airway inflammation. This…
Schlagworte
Asthma
Cytokine
Bronchoalveolar Lavage
Connective Tissue
Cytokines
Asthma bronchiale
Pneumologie
