BAL protein profile in smoking and no-smoking healthy subjects
P Rottoli, E Bargagli, A Carleo, C Olivieri, L Claudia, D Bennett, L Bini · Pneumologie · 2012 · Heft 11
Bibliografische Angaben
Zusammenfassung
Background: The proteomic approach is complementary to genomics and enables protein composition to be investigated under various clinical conditions. Its application to the study of bronchoalveolar lavage (BAL) is extremely promising. In the present research we applied the proteomic approach to the analysis of BAL in order to evaluate the effect of smoking exposure to BAL protein composition. Aim: Aim of this work was to evaluate qualitative and quantitative differences in BAL protein profiles from cigarette smoker and no-smoker healthy subjects. Methods: 10 healthy never-smoker and 8 asymptomatic smoker subject…