The stress-induced ligand MIC B and markers of apoptosis are up-regulated in patients with celiac disease as compared to NASH patients
J Kälsch, A Kahraman, M Schlattjan, T Marth, K Rehbehn, H Baba, G Gerken, A Canbay · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and Aims: Liver and gut not only share alimentary but also immunologically features. Major histocompatibility complex class I-related chains A and B (MIC A/B) function as indicators for cellular stress. These so called stress-induced ligands were suggested to play an important role in the progression of non-alcoholic fatty liver disease (NAFLD) and are also a prominent feature of celiac disease (CD). Patients and Methods: In the present study, 21 patients with celiac disease and 20 patients with non-alcoholic steatohepatitis (NASH) were investigated. Liver enzymes, markers of apoptosis (M30, M65), and…
