Bile: miRNA pattern and cell morphology as a diagnostic tool after liver transplantation
RB Schmuck, N Raschzok, A Reutzel-Selke, S Lippert, S König, KA Prabowo, MH Morgul, LM Tannus, S Jonas, P Neuhaus, IM Sauer · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aim: The international gold standard to detect acute rejection after liver transplantation (LTx) is liver biopsy, a procedure with considerable risks for the patient. Acute rejection is an immune response which causes inflammation and can mimic cholangitis, making the discrimination of those two disease challenging. In search for less invasive diagnostic tools, bile as a direct synthesis product of the transplanted liver may be analyzed in patients with external bile drain. microRNAs (miRNAs) are emerging as biomarkers for diagnosis and prediction of transplant rejection. The aim of our investigation was to stud…
