CareLit Fachartikel
Immune response guided treatment of severe lupoid autoimmune hepatitis
K Weigand, S Brost, CS Falk, J Pflaum, M Müller · Zeitschrift für Gastroenterologie · 2013 · Heft 01
Dokument
1141918
CareLit-ID
Jahr
2013
Publikation
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Zusammenfassung
Some cases of autoimmune hepatitis, especially non-typical cases, can not be treated easily. These cases are therapy refractory and need high doses of prednisolone to be controlled. Others are even non-responders to high dosis of steroids. We here present a rare case of most likely lupoid autoimmune hepatitis accompanied by Sjögren's syndrome in a 21-year old female, diagnosed by ANA titer of 1:10240, increased rheuma factors (172.5U/l) and total immunoglobuline G. In addition positive SS-A antibodies and positive Ro52 antibodies were detected. Histological findings showed minimal lymphocyte infiltration (Desmet…
Schlagworte
Hepatitis
Autoimmune Hepatitis
Antibodies
Autoimmune Diseases
Azathioprine
Budesonide
Cytokine
Zeitschrift für Gastroenterologie
