CareLit Fachartikel

Proanthocyanidin-enriched extract from Cranberry (Vaccinium macrocarpon Aiton) exhibits anti-invasive and not anti-adhesive activity against uropathogenic Escherichia coli (UPEC)

N Rafsanjany, A Hensel · Zeitschrift für Phytotherapie · 2013 · Heft 03

Dokument
1142149
CareLit-ID
Jahr
2013
Publikation
PDF
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Metadaten
DOI
ja
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Zeitschrift
Zeitschrift für Phytotherapie
Autor:innen
N Rafsanjany, A Hensel
Ausgabe
Heft 03 / 2013
Seiten
–
Erschienen: 2013-03-01 00:00:00
ISSN
0722-348X
DOI
10.1055/s-0033-1338188

Zusammenfassung

Urinary tract infections (UTIs) are one of the most common infectious diseases. 80% of UTIs are caused by UPEC. Rising antibiotic resistance and high recurrence rates are major problems of UTIs in clinical praxis. Therefore, the need for alternative therapies and prophylaxis is evident. Extracts from Cranberry fruits are traditionally used for prevention of recurrent UTIs and show considerably activity in clinical studies. The common opinion on the mode of action implies that A-type proanthocyanidins inhibit the adherence of UPEC to bladder epithelium by interacting with P-fimbriae and type 1 fimbriae (mannose s…

Schlagworte

Bacteria Bacterial Adhesion After Agglutination Belgium Agar Actin Zeitschrift für Phytotherapie