Environment sensing lipid based photo-accustic, MRI-optical tracer system validation in vitro and vivo models

Ziele: New nanoparticle and smart drug delivery agents are needed for imaging and theragnostic approaches. However there has been clear lack of probes that can be used simultaneously in molecular and organ level and that can bring light to the back ground accumulation to tumors (EPR) and active receptor mediated targeting.Here we describe a environment sensing multimodal photo-accustic MRI-optical tracer system that is promising due to a fact that they can give the anatomical information in tissue and organ level in animal models and in the same time give the precise information of the receptors and binding in c…