Health, marital and occupational state of patients with Crohn's disease relative to their non- IBD affected siblings and peers

Background: Health related quality of life (HRQoL), occupational and social life are impaired in patients with Crohn's disease (CD). Studies investigating the impact of CD on these components by direct comparison to non-IBD controls from a similar environment are missing. Methods: Hundered patients with CD and 40 non-IBD controls, recruited by the patients from their social environment, i.e. siblings and peers were included. Social, economic and HRQoL data, assessed by SF-12 and EQ-5D were compared between both groups. CD specific predictors for impaired HRQoL, including disease activity, measured by Harvey Brad…