CareLit Fachartikel
Neurocircuitry of Addiction: A brain reward deficit, stress surfeit and executive function disorder
G Koob · Suchttherapie · 2013 · Heft 09
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1142700
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Jahr
2013
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Zusammenfassung
Drug addiction has been hypothesized to be a chronically relapsing disorder of compulsive drug seeking and taking that progresses through three stages: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Drug addiction includes elements of positive reinforcement (binge/intoxication stage) and negative reinforcement (withdrawal/negative affect stage). The construct of negative reinforcement in addiction is defined as drug taking that alleviates a negative emotional state. The negative emotional state that drives such negative reinforcement is hypothesized to derive from dysregulation o…
Schlagworte
Reward
Executive Function
Amygdala
Anxiety
Affect
Suchttherapie
