Influence of heterogeneities on liver steatosis evaluation by Fibroscan® (CAP™): relevance of a liver guidance tool

Purpose: Controlled Attenuation Parameter (CAP) is a measure of ultrasound attenuation developed to assess steatosis on the Fibroscan®. CAP performance in clinical studies always showed satisfactory results. However, CAP is based on the hypothesis that liver parenchyma is homogeneous whereas it is not everywhere (blood vessel, nodules, etc.). The objective of here is to determine the influence of heterogeneities on CAP and show the clinical relevance of a liver guidance tool, developed to target the homogeneous parenchyma. Material and methods: Influence of heterogeneities was assessed on: Field II simulations:…