CareLit Fachartikel

Toxicological effects of functionalized Carbon Black Nanoparticles on Type II pneumocytes

N Schreiber, R Hochscheid, E Kotte, P Weber, B Müller · Pneumologie · 2013 · Heft 12

Dokument
1142947
CareLit-ID
Jahr
2013
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
N Schreiber, R Hochscheid, E Kotte, P Weber, B Müller
Ausgabe
Heft 12 / 2013
Seiten
–
Erschienen: 2013-12-09 00:00:00
ISSN
0934-8387
DOI
10.1055/s-0033-1357068

Zusammenfassung

Carbon black nanoparticle structures have been shown to influence the integrity of the respiratory tract, especially its surface functionalization is considered to structurally und functionally modulate the lung epithelia. To study the impact of functionalized carbon black nanoparticle surfaces a mouse model was established, applying the following particles by oropharyngeal aspiration: 9-nitroanthracen (NA) and benzo[a]pyren (BaP) functionalized and un-functionalized Printex®90 (7 µg), acetylene black with PAHs (7 and 15 µg) and DQ12 as positive control (7 µg). Saline as well as distilled water with and without…

Schlagworte

Acetylene Benzo(a)pyren Chemistry Cytokine After Pneumologie