Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival
B Goeppert, L Frauenschuh, M Zucknick, S Roessler, A Stenzinger, A Warth, C End, J Mollenhauer, M Vogel, A Mehrabi, M Hafezi, P Schirmacher, W Weichert, M Renner · Zeitschrift für Gastroenterologie · 2014 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: The secreted scavenger receptor cysteine-rich (SRCR) protein DMBT1 is differentially expressed in various cancer types and has been proposed to play a critical role in epithelial cell growth and cell differentiation. In biliary tract cancers (BTC) several risk factors, including cholangiolithiasis, liver fluke infection, and anatomical abnormalities, all associated with inflammation of the biliary tract, have been described. Therefore, the aim of the study was to analyze the expression of DMBT1 in BTC and to correlate the expression with clinicopathological data including patient survival. Methods: Tissue…
