CareLit Fachartikel

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

K Karimi, T Kessler, K Ramisch, E Tasika, P Arck, G Tiegs · Zeitschrift für Gastroenterologie · 2014 · Heft 01

Dokument
1143139
CareLit-ID
Jahr
2014
Publikation
PDF
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Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
K Karimi, T Kessler, K Ramisch, E Tasika, P Arck, G Tiegs
Ausgabe
Heft 01 / 2014
Seiten
–
Erschienen: 2014-01-13 00:00:00
ISSN
0044-2771

Zusammenfassung

Introduction: Liver disease can occur in the pregnant patient and pregnancy may occur in a patient with chronic liver disease, which in both cases severe consequences in the mother and fetus are expected. Prenatal risk factors may affect the development of allergies and human studies provided considerable indications for a correlation between the use of Acetaminophen (APAP) and an increased risk of the children to develop allergies. APAP is mainly metabolized in the liver, and freely crosses the placenta, resulting in pharmacologically active levels in the developing fetus. In the fetus, the liver transiently fu…

Schlagworte

Bronchoalveolar Lavage Acetaminophen Affect Asthma After Zeitschrift für Gastroenterologie