Prenatal ultrasonographic diagnosis of megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS)

Background: MMIHS is a system disorder with variable prognosis. Due to the lack of an early diagnosis infants with MMIHS frequently require surgery due to presumed intestinal obstruction. Aim: To establish criteria which enable prenatal diagnosis. Case report: During prenatal ultrasonography dilatation of the bladder and the ureters were seen at 32 weeks of gestation in the fetus of a 31 year old GII/PI with an otherwise unremarkable course of pregnancy. Additionally dilated bowel loops were visible without an obvious reason for intestinal obstruction. A Medline search for the combination of renal and intestinal…