CareLit Fachartikel
Establishment and validation of chromatin immunoprecipitation (ChIP) method for cohort studies
H Harb, D Kesper, H Renz, P Pfefferle · Pneumologie · 2014 · Heft 02
Dokument
1143265
CareLit-ID
Jahr
2014
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: Over the past few decades, the incidence of allergic diseases such as asthma has been increasing especially in westernized countries. This increase has been suggested to be of an environmental basis and might be triggered by epigenetic modifications. The aim of the work is to establish and validate a ChIP method suitable for cohort studies. To analyse epigenetic modifications like histone acetylation or histone methylation in samples e.g. cord blood cells, a redundant and validated method should be implemented. Methods: Chromatin Immunoprecipitation (ChIP) method was established for the measurement…
Schlagworte
Chromatin Immunoprecipitation
Chromatin
Asthma
Acetylation
Blood Cells
Blood
Work
Pneumologie
