Interim analysis of the early cosmetic outcome in the IMRT-MC2-trial

Cosmetic results have a significant impact on quality of life in breast cancer survivors. Several trials have shown that simple forward-planned intensity-modulated radiotherapy can improve cosmetic results in terms of global cosmetic outcome, reduced hyperpigmentation and a reduced risk of moist desquamation. The IMRT-MC2-trial is a phase III-randomized controlled trial comparing 3D-conformal radiotherapy with a sequential boost to inverse-planned intensity-modulated radiotherapy with a simultaneous integrated boost. Patients with breast cancer after breast-conserving surgery were randomized to 3D-conformal radi…