Longterm effect of vasolidator therapy in pulmonary hypertension due to chronic obstructive pulmonary disease. A retrospective analysis

Background: Pulmonary hypertension (PH) due to COPD has dismal prognosis. PH-target therapy may worsen ventilation-perfusion-mismatch and is insufficiently studied. We retrospectively analysed the long-term effect of PH-target therapy in COPD-PH. Methods: 493 patients attending our PH-clinic were reviewed for COPD-PH under vasodilator therapy. Baseline characteristics, death/transplantation until End 2013 and therapy, NYHA class, 6 minute walk distance (6MWD) and oxygen saturation (SpO2) at baseline, 3, 6, 12 and 24 months were noted. Results: Of 48 COPD-PH identified 21 were excluded (insufficient data, comorbi…